Multi-University Research Initiative (Office of Naval Research) Charan Ranganath, PI August 01, 2017 - July 30, 2022 A Computational Cognitive Neuroscience Approach to Understanding Event Representation and Episodic Memory
This program grant aims to develop a computational framework to explain how interactions between the hippocampus, ventromedial prefrontal cortex, and posterior medial network support event representation and episodic memory. We will accomplish the following Tasks: (1) Develop a computational model of event representation and episodic memory. (S. Gershman, Harvard), (2) Specify the neural mechanisms that support learning and application of semantic knowledge about events. (K. Norman, U. Hasson, Princeton), (3) Specify how cortico-hippocampal interactions support episodic memory retrieval and consolidation. (C. Ranganath, UC Davis), (4) Specify the cognitive and neural causes and consequences of event segmentation (J. Zacks, Washington University), & (5) Determine how broadband and oscillatory neural activity contributes to event segmentation and episodic memory (Orrin Devinsky & Lucia Melloni, NYU, in collaboration with all team members). Role: co-Principal Investigator
NSSEFF Ranganath, PI Office of Naval Research/Department of Defense February 01, 2015 – January 30, 2019 Decoding and Enhancing Neural Mechanisms for Episodic Memory
The goal of this project is to determine the causal role for theta oscillations in episodic memory. Three methods are proposed—transcranial alternating current stimulation, sensory entrainment, and reward motivation—to manipulate theta activity and determine the effects on memory for contextual details and corresponding effects on brain activity measured by fMRI and EEG. Role: Principal Investigator
1R01MH105411 Ranganath and Ragland, PIs NIMH December 01, 2014 – November 30, 2019 Neural Mechanisms of Memory Dysfunction in Schizophrenia
The goal of this proposal is to use multimodal imaging including magnetic resonance spectroscopy (MRS), electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) to determine the causes of memory deficits in schizophrenia. Role: Principal Investigator